Related Experiment Video

Updated: Aug 26, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

Analysis of infective endarteritis in patent ductus arteriosus

Masood Sadiq1, Farhan Latif, Asif Ur-Rehman

  • 1Department of Paediatric Cardiology, Punjab Institute of Cardiology, Lahore, Pakistan. drmasoodsadqui@hotmail.com

The American Journal of Cardiology
|February 19, 2004
PubMed

Insights

Infective endarteritis in children with patent ductus arteriosus often affects small ducts and is usually undiagnosed. Antibiotic treatment followed by closure is generally effective for this condition.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Patent ductus arteriosus (PDA) is a congenital heart defect.
  • Infective endarteritis is a rare but serious complication of PDA.
  • Diagnosis of infective endarteritis in small ducts can be challenging.

Purpose of the Study:

  • To report on the incidence and characteristics of infective endarteritis in children with PDA.
  • To evaluate the effectiveness of antibiotic treatment and subsequent closure for this condition.

Main Methods:

  • Retrospective review of 14 pediatric patients diagnosed with infective endarteritis and PDA over 6 years.
  • Analysis of clinical presentation, diagnostic findings, treatment protocols, and outcomes.

Main Results:

  • Infective endarteritis predominantly affected small, previously undiagnosed ducts.
  • All patients received antibiotic therapy for 4-10 weeks.
  • Successful closure was achieved in 13 out of 14 patients.

Conclusions:

  • Infective endarteritis is an underdiagnosed complication of PDA in children.
  • Prompt antibiotic treatment and surgical or interventional closure are crucial for successful management.
  • Early diagnosis and intervention can lead to favorable outcomes.

More Related Videos

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS08:12

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS

Published on: November 26, 2018

A New Murine Model of Endovascular Aortic Aneurysm Repair08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

Related Concept Videos

Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...