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Management of asymptomatic bacteriuria in patients with diabetes mellitus
Say-Tat Ooi1, Lawrence A Frazee, William G Gardner
1Akron General Medical Center, Akron, OH 44307, USA.
Objective:
To review the literature regarding the management of asymptomatic bacteriuria (ASB) in patients with diabetes mellitus.
Data Sources:
A MEDLINE (1967-June 2003) and bibliographic search of the English-language literature was conducted using the search terms diabetes mellitus, asymptomatic, bacteriuria, and urinary tract infection.
Data Synthesis:
ASB occurs in diabetic women more commonly than in non-diabetics and is associated with an increased risk of symptomatic urinary tract infection (UTI) among patients with type 2 diabetes. Symptomatic UTIs tend to follow a more complicated course in diabetics. Despite these independent observations, antimicrobial therapy has not been shown to reduce symptomatic UTIs, pyelonephritis, or hospitalization for UTI.
Conclusions:
Available evidence does not support antimicrobial treatment of ASB among patients with diabetes mellitus.
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