Related Experiment Video
Updated: Aug 26, 2026

10:21
Lentiviral Mediated Production of Transgenic Mice: A Simple and Highly Efficient Method for Direct Study of Founders
Published on: October 7, 2018
Use of natural and artificial chromosome vectors for animal transgenesis
Yoshimi Kuroiwa1, Kazuma Tomizuka, Isao Ishida
1Pharmaceutical Research Laboratory, Kirin Brewery Co, Ltd, Gunma, Japan.
Methods in Molecular Biology (Clifton, N.J.)
|February 19, 2004
Abstract
No abstract available in PubMed .
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Overview
In-vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

