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Updated: Aug 26, 2026

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP)
Published on: June 14, 2021
[Studies on the chemical structure of polysaccharide CDP-4 isolated from Cistanche deserticola]
1Peking University School of Pharmaceutical Sciences, Modern Research Center for Traditional Chinese Medicine, Beijing 100083, China.
Objective:
To study the chemical structure of polysaccharide CDP-4 isolated from Cistanche deserticola Y.C.Ma.
Methods:
The chemical properties of CDP-4 were determined by using chemical method and spectrocospic method.
Results:
CDP-4 was composed of glucosyl group, with the ratio 1,4-linkage glcp:1,6-linkage glcp=3:1,and its mean molecular weight 1.4 x 10(4). By means of methlylation analysis, complete acid hydrolysis analysis, NMR spectrum, the linkages and sequence information of CDP-4 were obtained.
Conclusion:
CDP-4 is a new linear glucan.
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