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[Chronic obstructive pulmonary disease: brief review].

Leonardo M Fabbri1, Micaela Romagnoli, Stefania Cossi

  • 1Sezione di Malattie dell'Apparato Respiratorio, Dipartimento di Scienze Mediche Oncologiche e Radiologiche, Università degli Studi di Modena e Reggio Emilia.

Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna
|February 20, 2004
PubMed
Summary

Chronic obstructive pulmonary disease (COPD) is a major cause of death and disability with significant socioeconomic costs. This review covers COPD

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Area of Science:

  • Respiratory Medicine
  • Pulmonology
  • Internal Medicine

Context:

  • Chronic obstructive pulmonary disease (COPD) presents significant global health challenges.
  • COPD is associated with emphysema and/or chronic bronchitis.
  • Rising mortality and morbidity rates underscore the urgency of understanding COPD.

Purpose:

  • To review current scientific knowledge on chronic obstructive pulmonary disease (COPD).
  • To highlight the clinical syndrome, including systemic manifestations.
  • To examine the pathogenesis and pathophysiology, focusing on airflow limitation and hyperinflation.

Summary:

  • This review synthesizes current scientific understanding of COPD.
  • It details the disease's nosography, clinical presentation, and systemic effects.

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  • Pathophysiological mechanisms, symptoms, and signs are discussed, emphasizing expiratory flow limitation and hyperinflation.

    • Impact:

    • Provides a comprehensive overview of COPD for clinicians and researchers.
    • Emphasizes the high socioeconomic burden of COPD.
    • Informs strategies for managing and mitigating COPD's impact.