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Updated: Aug 26, 2026

11:01
Application of Stopped-flow Kinetics Methods to Investigate the Mechanism of Action of a DNA Repair Protein
Published on: March 31, 2010
Protein-DNA interaction: impedance study of MutS binding to a DNA mismatch
Chen-Zhong Li1, Yi-Tao Long, Jeremy S Lee
1Department of Biochemistry, University of Saskatchewan, 107 Wiggins Road, Saskatoon, CanadaS7N 5E5.
Abstract:
MutS binding to a double-stranded DNA containing a single nucleotide mismatch can be conveniently monitored by impedance spectroscopy and represents the first step in developing an electrochemical binding essay for single nucleotide mismatch detection.
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