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Related Experiment Videos

Cranberries for preventing urinary tract infections.

R G Jepson1, L Mihaljevic, J Craig

  • 1Department of General Practice, Edinburgh University, 20 West Richmond Street, Edinburgh, UK, EH8 9DX.

The Cochrane Database of Systematic Reviews
|February 20, 2004
PubMed
Summary

Cranberry products may reduce symptomatic urinary tract infections (UTIs) in women over 12 months, but long-term adherence and optimal dosage remain unclear. Further research is needed to confirm effectiveness in diverse populations.

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Area of Science:

  • Urology
  • Natural Product Research
  • Evidence-Based Medicine

Background:

  • Cranberries have a long history of use for preventing and treating urinary tract infections (UTIs).
  • The effectiveness of cranberry products for UTI prevention requires rigorous assessment.

Purpose of the Study:

  • To evaluate the efficacy of cranberry juice and other cranberry preparations in preventing UTIs.
  • To assess cranberry product effectiveness in susceptible populations.

Main Methods:

  • Systematic review of randomized and quasi-randomized controlled trials.
  • Searched multiple databases and contacted manufacturers for relevant studies.
  • Extracted data on UTI incidence, side effects, and adherence; conducted meta-analysis where appropriate.

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Main Results:

  • Two high-quality RCTs showed cranberry products significantly reduced symptomatic UTIs in women over 12 months.
  • No significant difference was found between cranberry juice and capsules.
  • High dropout rates suggest potential issues with long-term adherence and acceptability.

Conclusions:

  • Evidence suggests cranberry juice may decrease symptomatic UTIs in women over a 12-month period.
  • Effectiveness in children and elderly populations is uncertain.
  • Optimal dosage and administration methods require further investigation.