Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Churg-Strauss syndrome].

Giovanni Garini1, Domenico Corradi, Augusto Vaglio

  • 1Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione, Università, Parma. garini@unipr.it

Recenti Progressi in Medicina
|February 21, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

EGPAware: a European Delphi consensus study on red flags for suspicion of eosinophilic granulomatosis with polyangiitis.

EULAR rheumatology open·2026
Same author

Glomeruloid haemangioma in Erdheim-Chester disease: An atypical skin manifestation associated with elevated vascular endothelial growth factor-A levels.

British journal of haematology·2026
Same author

Eculizumab for rapidly progressive glomerulonephritis in children.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Xanthogranulomatous Inflammatory Pelvic Mass Mimicking Malignancy: Successful Conservative Treatment and Narrative Insights into Diagnosis and Management.

Journal of clinical medicine·2026
Same author

A trial of hypoimmune allogeneic CD19-targeting T cells in refractory systemic lupus erythematosus.

Clinical kidney journal·2026
Same author

Current management of eosinophilic granulomatosis with polyangiitis across Europe: insights from a multinational expert survey.

Rheumatology (Oxford, England)·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
See all related articles

Churg-Strauss syndrome (CSS) is a rare allergic condition causing inflammation in blood vessels. Diagnosis relies on clinical and biopsy findings, with corticosteroids as the primary treatment.

Area of Science:

  • Rheumatology
  • Immunology
  • Pathology

Context:

  • Churg-Strauss syndrome (CSS), also known as eosinophilic granulomatosis with polyangiitis, is a rare systemic vasculitis.
  • It primarily affects individuals with a history of asthma or allergies and prominent eosinophilia.
  • While commonly involving the lungs, skin, and peripheral nerves, CSS can impact multiple organs.

Purpose:

  • To summarize the key characteristics, diagnostic criteria, and treatment strategies for Churg-Strauss syndrome.
  • To highlight the eosinophilic nature and complex pathophysiology of CSS.
  • To emphasize the diagnostic challenges due to the absence of specific biomarkers.

Summary:

  • CSS is characterized by peripheral blood eosinophilia, elevated serum IgE, and inflammatory markers.

Related Experiment Videos

  • Diagnosis is confirmed by correlating clinical manifestations with histological findings, including vasculitis and eosinophilic infiltration.
  • Antineutrophil cytoplasmic antibodies against myeloperoxidase are present in about half of patients.

    • Impact:

    • Effective management of CSS involves corticosteroids, often combined with cytotoxic agents like cyclophosphamide.
    • Refractory cases may benefit from treatments such as intravenous immunoglobulins or interferon-alpha.
    • Understanding CSS pathophysiology is crucial for developing targeted therapies and improving patient outcomes.