Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Preemptive analgesia does not reduce pain or improve postoperative functioning.

Jennifer O Grube1, Magdy P Milad, Jesse Damme-Sorenen

  • 1Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA.

JSLS : Journal of the Society of Laparoendoscopic Surgeons
|February 21, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bowel Injuries Reported After NovaSure Endometrial Ablation: A 10-Year Review of FDA MAUDE Data.

Journal of minimally invasive gynecology·2026
Same author

Effect of preoperative intravenous iron administration on transfusion outcomes in benign gynecologic surgery.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

Evaluation of ChatGPT and Gemini in Answering Patient Questions after Gynecologic Surgery.

Applied clinical informatics·2026
Same author

Losing our edge: how the decline of surgery is reshaping the specialty of reproductive endocrinology and infertility.

Fertility and sterility·2026
Same author

Comparing Proficiency of Laparoscopic Vaginal Cuff Suturing After Training with Two Simulators.

JSLS : Journal of the Society of Laparoendoscopic Surgeons·2026
Same author

Safe Without Suction: Double-Blind Randomized Controlled Trial Challenges Routine Gastric Decompression in Laparoscopy.

Journal of minimally invasive gynecology·2025

Preemptive analgesia using bupivacaine did not reduce postoperative pain for patients undergoing gynecologic laparoscopy. This study found no significant difference in pain scores or return to normal activities between groups.

Area of Science:

  • Anesthesiology
  • Gynecologic Surgery
  • Pain Management

Background:

  • Preemptive analgesia aims to reduce postoperative pain by administering analgesics before surgical incision.
  • Its effectiveness in gynecologic laparoscopy, a common surgical procedure, requires thorough investigation.

Purpose of the Study:

  • To evaluate the efficacy of preemptive analgesia in managing postoperative pain following gynecologic laparoscopy.
  • To determine if preemptive bupivacaine administration impacts pain perception and recovery time.

Main Methods:

  • A double-blinded, randomized controlled trial was conducted with 164 patients.
  • Patients received either 0.25% bupivacaine or a saline placebo preoperatively.
  • Pain scores, activity limitation, and narcotic consumption were assessed postoperatively.

Related Experiment Videos

Main Results:

  • No significant differences in overall or incisional pain scores were observed at 4 or 24 hours between the bupivacaine and placebo groups.
  • Activity limitation and oral narcotic consumption within 24 hours postoperatively were similar in both groups.
  • Stratified analysis by surgery complexity and logistic regression confirmed no significant outcome differences.

Conclusions:

  • Preemptive analgesia with bupivacaine is not effective in reducing postoperative pain after gynecologic laparoscopy.
  • The intervention did not accelerate the return to normal activities for patients undergoing these procedures.