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Published on: January 28, 2020
Secondary prevention for coronary artery disease
A L McLeod1, L Brooks, V Taylor
1Department of Cardiology, Ninewells Hospital, Dundee, UK. a.mcleod@ed.ac.uk
Insights
Secondary prevention of coronary artery disease shows improvement in medication adherence and smoking cessation. However, lifestyle factors like weight management require further attention for optimal cardiovascular risk reduction.
Area of Science:
- Cardiology
- Public Health
- Preventive Medicine
Background:
- Secondary prevention of coronary artery disease (CAD) is crucial for reducing patient morbidity and mortality.
- Identified challenges include implementation gaps and prescription biases in CAD secondary prevention.
Purpose of the Study:
- To evaluate the progress of secondary prevention strategies for coronary heart disease (CHD).
- To determine if differences exist in secondary prevention outcomes among patient subgroups (angina, post-myocardial infarction, revascularization).
Main Methods:
- Retrospective analysis of patient data collected between 1997 and 2001.
- Data included prophylactic prescribing, demographics, and lifestyle information at baseline and 1-year follow-up.
- Utilized a hospital-based, cardiac-nurse-led outpatient clinic for data collection.
Main Results:
- Significant increases observed in aspirin and statin prescribing, alongside improvements in lipid management (cholesterol < 5 mmol/l increased to 70%).
- Smoking cessation rates improved dramatically, with smokers reducing from ~30% to 10% by 2001.
- No significant changes in weight for patients with a Body Mass Index (BMI) >= 30; no significant differences found between patient subgroups.
Conclusions:
- Secondary prevention measures for CHD are advancing, particularly in medication adherence and smoking cessation.
- Further improvements are needed, especially in addressing lifestyle factors like weight management, to maximize cardiovascular risk reduction.
- No significant differences in outcomes were observed between patient subgroups, suggesting a need for consistent application of preventive strategies across diverse patient populations.
Background:
Secondary prevention of coronary artery disease is effective in reducing morbidity and mortality, but deficiencies in implementation and prescription bias have been identified.
Aim:
To assess progress in secondary prevention measures for coronary heart disease and whether there was a difference between patient subgroups with angina, post myocardial infarction or revascularization.
Design:
Retrospective analysis.
Methods:
Between 1997 and 2001, data were collected on prophylactic prescribing, demographic and lifestyle information, at baseline and 1 year following attendance at a hospital-based, cardiac-nurse-led out-patient clinic.
Results:
Patients (n = 945) were entered into the database at hospital discharge and 619 (72%) attended at 1 year. Aspirin and statin prescribing increased, though ACE inhibitor use was less. Mean total cholesterol at baseline reduced to 4.92 +/- 0.11 mmol/l (p < 0.001) in 2000, with a further reduction to 4.59 +/- 0.08 mmol/l at the 1-year visit in 2001 (p < 0.001). The proportion of patients with total cholesterol < 5 mmol/l increased to 38% in 2000, reaching 70% in 2001. Smokers at baseline were similar at around 30%, although this had reduced to 10% in 2001 (p < 0.001). No change in weight was seen for patients with BMI >or=30 (p = NS). No significant differences were seen between patient subgroups (p = NS).
Discussion:
Secondary prevention measures are improving, especially in prophylactic prescribing, lipid management and smoking cessation, although scope for further improvement remains. No difference was seen between the patient subgroups. Lifestyle measures need to be addressed to gain maximum benefit in addressing overall cardiovascular risk.
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