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Clinics in diagnostic imaging (93).

M Muttarak1, S Namwongprom, C Sivasomboon

  • 1Department of Radiology, Chiang Mai University, Chiang Mai, Thailand. mmuttara@mail.med.cmu.ac.th

Singapore Medical Journal
|February 21, 2004
PubMed
Summary

A parathyroid adenoma caused a patient's brown tumor and hypercalcemia, leading to a tibial fracture. Surgical removal confirmed the diagnosis, highlighting the importance of parathyroid imaging.

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Area of Science:

  • Endocrinology
  • Oncology
  • Radiology

Background:

  • Primary hyperparathyroidism is a condition characterized by excessive parathyroid hormone secretion.
  • It can lead to hypercalcemia, bone disease (like brown tumors), and kidney stones.
  • Parathyroid adenomas are the most common cause of primary hyperparathyroidism.

Observation:

  • A 63-year-old woman presented with a pathological tibial fracture secondary to a brown tumor.
  • She also had hypercalcemia and a thyroid soft tissue mass.
  • Neck ultrasound revealed a well-circumscribed, heterogeneously hypoechoic mass displacing the right thyroid lobe.

Findings:

  • Histopathological examination of the excised specimen confirmed a parathyroid adenoma.
  • The patient's symptoms were attributed to primary hyperparathyroidism caused by the adenoma.

Implications:

  • This case underscores the diverse clinical manifestations of primary hyperparathyroidism.
  • Accurate imaging of the parathyroid glands is crucial for diagnosis and management.
  • Timely surgical intervention for parathyroid adenomas can resolve associated complications.

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