Related Experiment Videos
A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding
G O Pflugfelder1, H Roth, B Poeck
1Theodor-Boveri-Institut, Lehrstuhl für Genetik, Würzburg, Germany.
Biochemical and Biophysical Research Communications
|July 31, 1992
Abstract:
The distribution of sequence elements divides the optomotor-blind protein into three regions and is suggestive of a transcriptional regulatory role of this protein. The central region of Omb is homologous to the N-terminal half of the Brachyury protein. The conserved domain of Omb is here shown to possess general DNA binding affinity but has no significant similarity to recognized DNA binding motifs.