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Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
Published on: June 9, 2017
[Neurotoxic effect of 7,8-oxide styrene on striatal neuron culture]
1Dipartimento di Medicina interna e Medicina pubblica, Università di Bari.
Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia
|February 26, 2004
Abstract:
The present study was undertaken to test the hypothesis that the neurotoxic action of styrene may be primarily presynaptic in nature and may involve impaired regulation of DA content and stimulation of DA release. Primary striatal neurons were grown in vitro and exposed to styrene oxide at different concentrations to evaluate the minimal effective dose able to induce these synaptic alterations.
