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Monovalent cation transport in irreversibly sickled cells

M R Clark, C E Morrison, S B Shohet

    The Journal of Clinical Investigation
    |August 1, 1978
    PubMed
    Summary

    Sickle cell blood cells (ISCs) show reduced active transport of cations. This occurs despite normal Na, K-ATPase activity in ISC membranes, suggesting internal cellular factors inhibit cation transport in sickle cell disease.

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