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Related Experiment Videos

Acid reflux management: ENT perspective.

Ijaz Ahmad1, A J G Batch

  • 1Department of Otolaryngology, Birmingham City Hospital, Birmingham, UK. ijazmad@hotmail.com

The Journal of Laryngology and Otology
|February 26, 2004
PubMed
Summary
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Laryngopharyngeal reflux (LPR) symptoms like voice change and globus are reliable indicators for diagnosis and successful treatment with proton pump inhibitors (PPIs). Flexible oesophago-gastroscopy is a valuable diagnostic tool for LPR.

Area of Science:

  • Otolaryngology
  • Gastroenterology
  • Digestive Health

Background:

  • Laryngopharyngeal reflux (LPR) presents with diverse pharyngeal and laryngeal symptoms.
  • Identifying reliable diagnostic indicators and treatment responses in LPR patients is crucial.

Purpose of the Study:

  • To identify the most reliable symptoms and signs of LPR.
  • To evaluate the diagnostic utility of flexible oesophago-gastroscopy (FOG) in LPR.
  • To assess treatment response to proton pump inhibitors (PPIs) in LPR patients.

Main Methods:

  • A prospective study of 303 patients with suspected LPR symptoms.
  • Flexible oesophago-gastroscopy (FOG) was performed for diagnosis.
  • Symptom improvement was measured on a 0-100% scale after PPI treatment.

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Main Results:

  • Globus, voice change, sore throat, dysphagia, and cough were predominant LPR symptoms.
  • FOG revealed abnormalities in 98% of patients; laryngeal lesions were uncommon.
  • 76.8% of patients responded to PPI treatment, with significant predictors including globus and voice change.

Conclusions:

  • Voice change, sore throat, globus, and cough are reliable LPR symptoms.
  • Globus and voice change predict successful PPI treatment response.
  • FOG is a safe and effective diagnostic method for LPR, and PPIs are effective for most patients.