Related Experiment Video
Updated: Aug 26, 2026

Bacterial Expression and Purification of Human Matrix Metalloproteinase-3 using Affinity Chromatography
Published on: March 30, 2022
New heteroarylbenzenesulphonamides as matrix metalloproteinase inhibitors
Frédéric Delbecq1, Guy Cordonnier, Nicole Pommery
1Groupe de Recherches sur l'Inhibition de la Prolifération Cellulaire UPRES EA 2692, Equipe de Chimie Organique, Université des Sciences et Technologies de Lille, F-59655 Villeneuve d'Ascq, France.
Abstract:
A series of derivatives of 2,4- and 2,5-thiazolyl- or oxazolylbenzenesulphonamides has been prepared and evaluated as potential MMP inhibitors. The thiazole 15b have been found to exhibit MMP-2 and MMP-9 inhibitions higher than reference compounds GI 129471 and CGS 27023A.
Related Concept Videos
Role of Matrix Metalloproteases in Degradation of ECM
A...
Preparation and Reactions of Sulfides

