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Updated: Aug 6, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
Pathology of squamous carcinomas of the head and neck
1Royal Marsden Hospital, Sutton, Surrey, UK.
Abstract:
Recent publications have been critically reviewed to illustrate some of the newer approaches that may eventually provide more precise prognostic information from tumor biopsies. Examples include changes in expression of various surface antigens, DNA ploidy, and alterations at the level of molecular genetics, eg, gene amplification. Other molecular changes in tumor tissue, such as point mutations and loss of normal tumor suppressor genes, are also giving clues to underlying carcinogenic mechanisms.
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