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MNGIE neuropathy: five cases mimicking chronic inflammatory demyelinating polyneuropathy
Richard S Bedlack1, Tuan Vu, Simon Hammans
1Division of Neurology, Duke University Medical Center, 932 Morreene Road, Box 3333, Durham, North Carolina 27707, USA. Bedla001@mc.duke.edu
Muscle & Nerve
|February 26, 2004
Abstract:
We report five patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) who had demyelinating peripheral neuropathy. The MNGIE neuropathy had clinical and electrodiagnostic features typical of acquired, rather than inherited, etiologies. In fact, three patients were actually treated for chronic inflammatory demyelinating polyneuropathy (CIDP). We discuss findings that may help distinguish patients with MNGIE from those with CIDP.