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Related Experiment Videos

Quantitative comparisons between a nicotine delivery device (Eclipse) and conventional cigarette smoking.

Eun M Lee1, Jennifer L Malson, Eric T Moolchan

  • 1National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA.

Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco
|February 26, 2004
PubMed
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The Eclipse nicotine delivery device (NDD) delivered less nicotine but more carbon monoxide than conventional cigarettes. This NDD was rated as less satisfying and more aversive by users.

Area of Science:

  • Tobacco regulatory science
  • Nicotine and tobacco research
  • Public health

Background:

  • R. J. Reynolds introduced the Eclipse nicotine delivery device (NDD) in 1997, claiming reduced smoke exposure compared to conventional cigarettes.
  • The Eclipse NDD utilizes a carbon fuel element to vaporize nicotine, delivering it as vapor to the user.

Purpose of the Study:

  • To compare the effects of the Eclipse NDD versus conventional cigarettes (Own Brand) on smoking topography, substance delivery, and physiological, subjective, and biochemical markers.
  • To evaluate the efficacy of a topography device in quantifying smoke exposure from NDDs.

Main Methods:

  • Ten adult smokers used the Eclipse NDD and Own Brand cigarettes under conventional and topography mouthpiece conditions.
  • Smoking behavior, exhaled carbon monoxide (CO), plasma nicotine levels, and subjective ratings were measured before and after smoking sessions.

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  • Data were collected over five separate sessions for each participant, with at least 24 hours between sessions.

    • Main Results:

    • The Eclipse NDD took longer to smoke (366s vs. 292s) and required more puffs (14.8 vs. 10.8) than Own Brand.
    • Exhaled CO increased more with the NDD (7.3 ppm vs. 4.2 ppm), while plasma nicotine boost was higher with Own Brand (16.4 ng/ml vs. 10.7 ng/ml).
    • Users rated the NDD as less satisfying, less rewarding, and more aversive than their own brand cigarettes.

    Conclusions:

    • The Eclipse NDD delivers significant amounts of nicotine and carbon monoxide, alongside potential harmful tobacco smoke components.
    • Despite claims, the NDD did not reduce exposure to harmful substances compared to conventional cigarettes.
    • The study validated the use of topography devices for accurately measuring smoke exposure from novel nicotine delivery devices.