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[Treatment of serious infectious diseases in children]

Lars Krogvold1, Karl-Olaf Wathne

  • 1Seksjon for infeksjonssykdommer, Barnemedisinsk avdeling, Ullevål universitetssykehus, Oslo. lars.krogvold@ulleval.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|February 26, 2004
PubMed

Insights

New guidelines for treating serious pediatric infections propose once-daily aminoglycosides and higher aciclovir doses for herpes simplex encephalitis, promoting antibiotic resistance prevention.

Area of Science:

  • Pediatric Infectious Diseases
  • Pharmacology
  • Antimicrobial Stewardship

Context:

  • Serious systemic infections pose significant challenges in pediatric care.
  • Effective treatment guidelines are crucial for managing pediatric infections.
  • Antibiotic resistance is a growing global health concern.

Purpose:

  • To propose updated treatment guidelines for serious pediatric infectious diseases.
  • To recommend specific dosage adjustments for key antimicrobial agents.
  • To advocate for a conservative antibiotic policy to combat resistance.

Summary:

  • Guidelines suggest once-daily dosing for aminoglycosides in pediatric patients.
  • Increased dosage of aciclovir is recommended for treating herpes simplex encephalitis.
  • The proposals aim to optimize treatment while minimizing resistance development.

Impact:

  • Potential to improve treatment efficacy for serious pediatric infections.
  • Contributes to a more sustainable and environmentally conscious antibiotic strategy.
  • Supports global efforts in antimicrobial stewardship and resistance prevention.
Abstract

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