Bcl-2 initiates a new category of oncogenes: regulators of cell death

Tuberin activates the proapoptotic molecule BAD.

Oncogene·2006

BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma.

Oncogene·2006

Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice.

British journal of cancer·2004

Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons.

Cell death and differentiation·2004

BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.

Developmental biology·2002

BAX contributes to apoptotic-like death following neonatal hypoxia-ischemia: evidence for distinct apoptosis pathways.

Molecular medicine (Cambridge, Mass.)·2002

KPNA2-Mediated MYC Nuclear Import Enhances CAR-T Cell Memory and Potentiates Antitumor Efficacy.

Blood·2026

How I Identify and Diagnose Carriers of Hemophilia and Women and Girls with Hemophilia.

Blood·2026

The origins of rare glycosylphosphatidylinositol-deficient cells in normal and immune-mediated hematopoiesis.

Blood·2026

How I Treat Heavy Menstrual Bleeding in Patients with Bleeding Disorder of Unknown Cause.

Blood·2026

Choice of a different donor reduces relapse risk after second allogeneic SCT for MDS.

Blood·2026

A multicenter phase II study of glofitamab plus polatuzumab-R-CHP for patients with diffuse large B-cell lymphoma.

Blood·2026

Senomorphic miR-3155b suppresses the senescence-associated secretory phenotype in therapy-induced senescence.

Frontiers in cell and developmental biology·2026

Predictive biomarkers for precision treatment in rheumatoid arthritis: are we there yet?

Frontiers in pharmacology·2026

Breaking the ERK1/2 negative feedback loop: avoiding reactivation and acquisition of resistance by ERK1/2 to anti-cancer agents.

Frontiers in oncology·2026

Clinical trial landscape and translational priorities for adoptive T-cell and NK-cell therapies in gynecologic malignancies.

Frontiers in immunology·2026

Oncolytic reovirus: tumor-microenvironment remodeling, engineering constraints, and translational strategies.

Frontiers in immunology·2026

Profiling crystal engineered ligands for targeting treatment resistant androgen receptors.

Frontiers in pharmacology·2026

Related Experiment Videos

Bcl-2 initiates a new category of oncogenes: regulators of cell death

Related Concept Videos

Tuberin activates the proapoptotic molecule BAD.

BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma.

Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice.

Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons.

BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.

BAX contributes to apoptotic-like death following neonatal hypoxia-ischemia: evidence for distinct apoptosis pathways.

KPNA2-Mediated MYC Nuclear Import Enhances CAR-T Cell Memory and Potentiates Antitumor Efficacy.

How I Identify and Diagnose Carriers of Hemophilia and Women and Girls with Hemophilia.

The origins of rare glycosylphosphatidylinositol-deficient cells in normal and immune-mediated hematopoiesis.

How I Treat Heavy Menstrual Bleeding in Patients with Bleeding Disorder of Unknown Cause.

Choice of a different donor reduces relapse risk after second allogeneic SCT for MDS.

A multicenter phase II study of glofitamab plus polatuzumab-R-CHP for patients with diffuse large B-cell lymphoma.

Senomorphic miR-3155b suppresses the senescence-associated secretory phenotype in therapy-induced senescence.

Predictive biomarkers for precision treatment in rheumatoid arthritis: are we there yet?

Breaking the ERK1/2 negative feedback loop: avoiding reactivation and acquisition of resistance by ERK1/2 to anti-cancer agents.

Clinical trial landscape and translational priorities for adoptive T-cell and NK-cell therapies in gynecologic malignancies.

Oncolytic reovirus: tumor-microenvironment remodeling, engineering constraints, and translational strategies.

Profiling crystal engineered ligands for targeting treatment resistant androgen receptors.

Related Experiment Videos

Bcl-2 initiates a new category of oncogenes: regulators of cell death

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