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Updated: Aug 26, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[Analysis of pathogenic relations between dental caries and periodontitis]
De-yi Li1, Jing-jing Guo, Jun-jun Zhao
1Department of Oral Medicine, Ninth People's Hospital, Shanghai Second Medical University, Shanghai, 200011, China.
Objective:
In order to search the cause of dental caries and periodontitis.
Methods:
Selected 70 patients with severe chronic periodontitis (CP group) and 50 patients with caries sensitivity (CS group) in clinical adults of oral medicine (18 to 50-year-old) during 1 year. Parameters of oral hygiene, caries and periodontitis were recorded in the typical groups of CP and CS.
Results:
The patients of CP group had rare caries, DFS in the groups of CP and CS was 1.46+/-2.60 and 17.32+/-7.55 respectively(p<0.001),while the patients of CS group had relative periodontal health indeed, CPTNI in CS and CP groups were 0.98+/-0.63 and 3.24+/-0.62 respectively (p<0.001), and the number of missing teeth was 1.90+/-3.34 and 1.10+/-1.85 respectively(p>0.05). 3 patients(only 2.4%)confirmed the parameters of caries sensitive as well as severe periodontitis.
Conclusion:
The correlating pathogenesis of caries and periodontitis seems to have antiagonism tendency. The ecological connection and bacterial interaction are worthy of further study.
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