Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic intrathecal catheterization in the sheep.

A E Kyles1, A Waterman, A Livingston

  • 1Department of Veterinary Surgery, University of Bristol, England, Great Britain.

Journal of Pharmacological and Toxicological Methods
|May 1, 1992
PubMed
Summary

Researchers developed a straightforward method for implanting intrathecal catheters in sheep. This technique achieved a 60% success rate for chronic catheter placement, crucial for long-term studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrospective study to estimate the prevalence and describe the clinicopathological characteristics, treatments received, and outcomes of HER2-low breast cancer.

ESMO open·2023
Same author

Antinociceptive effects of intrathecal 5-HT agonists in sheep.

Veterinary anaesthesia and analgesia·2017
Same author

Assessing experimental visceral pain in dairy cattle: A pilot, prospective, blinded, randomized, and controlled study focusing on spinal pain proteomics.

Journal of dairy science·2014
Same author

The effects of droperidol on fentanyl-induced dysphoria in the sheep.

Journal of psychopharmacology (Oxford, England)·2012
Same author

The effect of low-dose droperidol on fentanyl analgesia in sheep.

Journal of psychopharmacology (Oxford, England)·2012
Same author

Pharmacokinetics and pharmacodynamics of A77 1726 and leflunomide in domestic cats.

Journal of veterinary pharmacology and therapeutics·2011

Area of Science:

  • Veterinary Surgery
  • Neurosurgery
  • Animal Models

Background:

  • Chronic intrathecal drug delivery requires reliable catheter implantation.
  • Previous methods may be invasive or lack long-term functionality.

Purpose of the Study:

  • To describe a simple, noninvasive method for chronic intrathecal catheter implantation in sheep.
  • To assess the success rate and long-term viability of implanted catheters.

Main Methods:

  • A novel technique for chronic intrathecal catheter implantation was performed in nine sheep (17 attempts).
  • Catheter placement and integrity were confirmed using radiography with contrast medium.

Main Results:

  • The technique resulted in a 60% success rate for correctly positioned, functional intrathecal catheters.

Related Experiment Videos

  • Successfully implanted catheters were maintained for up to 16 months without complications.

    • Conclusions:

    • This method offers a viable approach for chronic intrathecal catheterization in sheep.
    • The technique demonstrates good long-term functionality and reliability for research applications.