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[Case report: lymphosarcoma in a cow].

M Schell1, H P Heckert, K E Müller

  • 1Klinik für Klauentiere, Freien Universität Berlin.

DTW. Deutsche Tierarztliche Wochenschrift
|February 27, 2004
PubMed
Summary

A sporadic lymphosarcoma case in a cow presented with orbital tumors and enlarged lymph nodes. Diagnostic tests ruled out bovine leucosis virus, indicating a non-viral lymphosarcoma etiology.

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Area of Science:

  • Veterinary Pathology
  • Oncology
  • Animal Health

Background:

  • Lymphosarcoma is a significant neoplastic disease in cattle.
  • Sporadic cases can occur independently of enzootic bovine leucosis virus (BLV).
  • Understanding non-BLV associated lymphosarcoma is crucial for differential diagnosis.

Observation:

  • A cow presented with a tumorous mass in the right orbital region and conjunctival edema.
  • Clinical examination revealed enlarged superficial and deep lymph nodes.
  • Hematological and clinicochemical analyses showed minimal changes, including a slight shift to the right in the white blood cell count.

Findings:

  • Bovine serum was negative for antibodies against bovine leucosis virus (BLV).
  • Necropsy confirmed leucotic and tumorous infiltrations in multiple organs.
  • The case represents sporadic lymphosarcoma, distinct from BLV-induced lymphoproliferative disease.

Implications:

  • This case highlights the importance of considering sporadic lymphosarcoma in cattle, even with negative BLV serology.
  • Accurate diagnosis is essential for appropriate herd management and disease control strategies.
  • Further research into the pathogenesis of sporadic lymphosarcoma in cattle is warranted.

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