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Duplex screening for asymptomatic carotid artery disease in Hispanic diabetic patients undergoing lower extremity
W Tracey Jones1, Boulos Toursarkissian, Marcus Dayala
1Division of Vascular Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA.
Insights
Screening for carotid artery disease in diabetic Hispanic patients with critical limb ischemia is not routinely recommended. However, older patients may benefit from screening for moderate stenosis to monitor disease progression.
Area of Science:
- Vascular Surgery
- Cardiovascular Disease
- Diabetology
Background:
- Systemic atherosclerosis screening, including carotid artery disease, is recommended for patients with peripheral or coronary artery disease.
- Anecdotal observations suggest a unique atherosclerotic pattern in South Texas Hispanic patients.
Purpose of the Study:
- To determine the prevalence of significant carotid artery disease in Hispanic patients with diabetes and limb-threatening ischemia.
- To identify predictive factors for carotid artery disease in this population.
Main Methods:
- Prospective study of 92 consecutive patients undergoing infrainguinal bypass for limb salvage.
- Perioperative color duplex scanning to assess internal carotid artery velocities.
- Correlation analysis with patient demographics and clinical findings.
Main Results:
- Carotid artery stenosis presence did not correlate with most variables, except advanced age and bruit.
- Only 2 patients (2.2%) had greater than 80% stenosis.
- Moderate stenosis (peak systolic velocity >175 cm/sec) was identified in older patients.
Conclusions:
- Routine carotid artery disease screening is not justified in younger diabetic Hispanic patients with critical lower extremity ischemia.
- High-grade stenosis requiring intervention is unlikely in older patients in this cohort.
- Screening older patients for moderate stenosis is recommended for monitoring potential progression.
Abstract:
Screening for carotid artery disease in patients with systemic manifestations of atherosclerosis (e.g., peripheral vascular disease or coronary artery disease) has been recommended. We have been anecdotally impressed by what appears to be a unique atherosclerotic disease pattern in the Hispanic patient population of South Texas. To determine the prevalence of significant carotid artery disease in Hispanic patients with diabetes presenting with limb-threatening ischemia and to identify factors predictive of occurrence, we conducted a year-long prospective study of 92 consecutive patients undergoing infrainguinal bypass for limb salvage at The University of Texas Health Science Center in San Antonio. Peak systolic and end diastolic velocities in both internal carotid arteries were recorded by perioperative color duplex scanning. We found that the presence of a carotid artery stenosis did not correlate with any variables other than advanced age and presence of a bruit. Only 2 patients had a greater than 80% stenosis. We concluded that screening for carotid artery disease in diabetic Hispanics with critical lower extremity ischemia cannot be justified in younger patients. Even in patients older than 60 years, the presence of high-grade stenosis and, therefore, the need for carotid endarterectomy, is unlikely. However, screening in older patients is recommended to identify persons with moderate stenosis (peak systolic velocity greater than 175 cm/sec) whose disease is more likely to progress.
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