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GPI-1485 (Guilford).

Victoria L Marshall¹, Donald G Grosset

¹Southern General Hospital, Department of Neurology, Institute of Neurological Sciences, 1345 Govan Road, Glasgow G51 4TF, UK.

Current Opinion in Investigational Drugs (London, England : 2000)

|February 27, 2004

Summary

This summary is machine-generated.

Guilford

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Area of Science:

Neuroscience
Pharmacology

Background:

Neuroimmunophilin ligands modulate cellular processes.
FK-506-binding proteins are key targets for therapeutic intervention.

Purpose of the Study:

To evaluate the therapeutic potential of GPI-1485.
To investigate GPI-1485 for Parkinson's disease and erectile dysfunction.

Main Methods:

Phase II clinical trials were initiated.
Investigational drug GPI-1485 was administered to participants.

Main Results:

Clinical trials commenced for Parkinson's disease in 2002.
Clinical trials commenced for erectile dysfunction in 2003.

Conclusions:

GPI-1485 is under clinical investigation for neurological and urological conditions.
Further research is warranted to establish efficacy and safety.