Related Experiment Video
Updated: Aug 26, 2026

Modeling and Experimental Analysis of the Single-Shaft Coaxial Motor-Pump Assembly in Electrohydrostatic Actuators
Published on: June 13, 2022
Harmonic analysis of perfusion pumps
F Carroll Dougherty1, F M Donovan, Mary I Townsley
1Department of Mechanical Engineering, EGCB 204, University of South Alabama, Mobile, AL 36688, USA. doughert@jaguar1.usouthal.edu
Abstract:
The controversy over the use of nonpulsatile versus pulsatile pumps for maintenance of normal organ function during ex vivo perfusion has continued for many years, but resolution has been limited by lack of a congruent mathematical definition of pulsatility. We hypothesized that the waveform frequency and amplitude, as well as the underlying mean distending pressure are all key parameters controlling vascular function. Using discrete Fourier Analysis, our data demonstrate the complexity of the pulmonary arterial pressure waveform in vivo and the failure of commonly available perfusion pumps to mimic in vivo dynamics. In addition, our data show that the key harmonic signatures are intrinsic to the perfusion pumps, are similar for flow and pressure waveforms, and are unchanged by characteristics of the downstream perfusion circuit or perfusate viscosity.
More Related Videos
Related Concept Videos
Steady, Laminar Flow Between Parallel Plates
Node Analysis for AC Circuits
To unravel the complexities of this system, nodal analysis is employed, a powerful technique founded on Kirchhoff's current law (KCL), which remains valid for phasors. AC circuits can effectively be...
The Power Flow Problem and Solution
Dimensional Analysis
In fluid mechanics, dimensional...
Steady, Laminar Flow in Circular Tubes

