Related Experiment Video
Updated: Aug 26, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Therapeutic specifics in atrial fibrillation in hyperthyroidism. Study of 14 cases]
Myrvat Kamoun1, Maher Haffani, Leila Basdeh
1Service de Médecine Interne B, Hôpital Charles Nicolle, Tunis.
Insights
This study on hyperthyroidism and atrial fibrillation found that treating the thyroid condition quickly improves arrhythmia outcomes. Factors like age and valvular disease negatively impact recovery.
Area of Science:
- Cardiology
- Endocrinology
Background:
- Atrial fibrillation (AF) is a common arrhythmia, and hyperthyroidism is a known risk factor.
- Understanding the specific interplay between hyperthyroidism and AF is crucial for effective patient management.
Observation:
- This retrospective study analyzed 14 patients hospitalized for hyperthyroidism with atrial fibrillation.
- Common symptoms included palpitations and dyspnea; 83.3% had valvular disease detected via echocardiography.
- Cardiovascular complications occurred in 5 patients, including heart failure and cardiomyopathy.
Findings:
- Treatment for hyperthyroidism included radio-iodine (7 patients) and thyroidectomy (2 patients).
- Arrhythmia management involved propranolol and anticoagulation.
- Among 9 recovered hyperthyroid patients, only 3 showed arrhythmia reduction, often associated with older age and longer arrhythmia history.
Implications:
- Achieving euthyroidism or hypothyroidism rapidly improves chances of treating associated atrial fibrillation.
- Factors such as advanced age, pre-existing valvular disease, and left atrial dilation are associated with poorer outcomes.
- Early and effective management of hyperthyroidism is key to resolving atrial fibrillation.
Abstract:
The aim of this study is to clarify the specificities of atrial fibrillation in hyperthyroidism. It's a retrospective study of 6 years, about 14 patients hospitalized for hyperthyroidism with atrial fibrillation. There were 9 Women and 5 men, 55.7 +/- 11.5 years old. Arryhthmia was discovered especially with palpitation and dyspnea. Cardiac echography diagnosed valvular disease in 83.3% of cases. Cardiovascular complications concerned 5 patients and consisted in cardiac insufficiency and cardiomyopathy in one case. Treatment of hyperthyroid consisted in radio-iodine administered to 7 patients at the dose of 9.8 +/- 3.9 mCi. Two patients had total thyroidectomy. Arryhthmia was treated with propranolol, 98.3 +/- 70 mg daily and anticoagulant treatment was given. From the group of nine hyperthyroid recovered patients, arryhthmia was reduced in 3 cases. In this group, age was higher and arryhthmia history was longer. We conclude that chances to treat arryhthmia associated to hyperthyroid are higher when euthyroidism or even hypothyroidism is rapidly obtained, during of atrial evolution is short and some factors aren't present, like aging, existence of valvular disease or left auricular dilatation.
Related Concept Videos
Hyperthyroidism II: Pathophysiology
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Hyperthyroidism I: Introduction
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Dysrhythmias VI: Management of Dysrhythmias
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
