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Hypothalamic electrical activity that relates to the pulsatile release of luteinizing hormone exhibits diurnal
H Hiruma1, M Nishihara, F Kimura
1Department of Physiology, Yokohama City University School of Medicine, Japan.
Brain Research
|June 5, 1992
Abstract:
The multiunit activity (MUA) was recorded in the arcuate nucleus-median eminence region in freely moving ovariectomized rats maintained under controlled lighting conditions (lights on 05.00-19.00 h) over a period of 24 h. The MUA of each rat had been confirmed to exhibit characteristic increases (volleys) in association with pulses of luteinizing hormone. In 6 MUAs examined, the frequency of MUA volleys was significantly greater in the dark period than in the light period, suggesting a diurnal variation in the release of luteinizing hormone-releasing hormone in the ovariectomized rat.