Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

PROFILEGRAPH: an interactive graphical tool for protein sequence analysis.

K Hofmann1, W Stoffel

  • 1Institute für Biochemie, Medizinische Fakultät der Universität zu Köln, Germany.

Computer Applications in the Biosciences : CABIOS
|August 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revealing the quantum nature of the voltage-induced conductance changes in oxygen engineered yttrium oxide-based RRAM devices.

Scientific reports·2024
Same author

RNase 7 downregulates TH2 cytokine production by activated human T cells.

Allergy·2017
Same author

Fish or n3-PUFA intake and body composition: a systematic review and meta-analysis.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2014
Same author

Depression in early adulthood: prevalence and psychosocial correlates among young Swiss men.

Swiss medical weekly·2014
Same author

Clock gene expression in the liver of streptozotocin-induced and spontaneous type 1 diabetic rats.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2013
Same author

GLUT4 in the endocrine pancreas--indicating an impact in pancreatic islet cell physiology?

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2012
Same journal

DCA: an efficient implementation of the divide-and-conquer approach to simultaneous multiple sequence alignment.

Computer applications in the biosciences : CABIOS·1998
Same journal

Two applications to facilitate the viewing of database search result files on the Macintosh.

Computer applications in the biosciences : CABIOS·1998
Same journal

BioWish: a molecular biology command extension to Tcl/Tk.

Computer applications in the biosciences : CABIOS·1998
Same journal

The Sequence Alerting Server--a new WEB server.

Computer applications in the biosciences : CABIOS·1998
Same journal

A software tool for the analysis of mass spectrometric disulfide mapping experiments.

Computer applications in the biosciences : CABIOS·1998
Same journal

SAMBA: hardware accelerator for biological sequence comparison.

Computer applications in the biosciences : CABIOS·1998
See all related articles

PROFILEGRAPH is a user-friendly tool that integrates various sliding-window methods for amino acid sequence analysis. It enables flexible parameter combination and visualization, aiding in protein structure analysis.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Structural Biology

Background:

  • Amino acid sequence analysis is crucial for understanding protein function and structure.
  • Existing tools often lack flexibility in integrating diverse analytical methods.
  • A unified, user-friendly platform is needed for advanced sequence analysis.

Purpose of the Study:

  • To introduce PROFILEGRAPH, a novel graphical interactive tool for analyzing amino acid sequences.
  • To integrate multiple sliding-window methods into a single, cohesive software.
  • To provide enhanced visualization and analysis capabilities for protein primary structures.

Main Methods:

  • Development of a graphical user interface (GUI) for interactive analysis.
  • Integration of various sliding-window algorithms for sequence data.

Related Experiment Videos

  • Implementation of customizable parameter-to-analysis combinations.
  • Inclusion of utilities for visual analysis, such as helical-wheel diagrams.

    • Main Results:

    • PROFILEGRAPH successfully integrates diverse sliding-window methods into a single shell.
    • Users can combine amino acid parameters with various analysis types for flexible plotting.
    • The tool facilitates calculation and visualization of moments relative to secondary structures.
    • Adaptability to most published sliding-window analysis procedures is demonstrated.

    Conclusions:

    • PROFILEGRAPH offers a versatile and user-friendly platform for in-depth amino acid sequence analysis.
    • The program enhances the visual and quantitative exploration of protein primary structures.
    • It supports the adaptation and application of a wide range of bioinformatic analysis techniques.