Total synthesis of the novel NF-kappaB inhibitor (-)-cycloepoxydon
Goverdhan Mehta1, Kabirul Islam
1Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India. gm@orgchem.iisc.ernet.in
Organic Letters
|February 28, 2004
Abstract:
An enantioselective total synthesis of the novel, biologically active epoxyquinone natural product (-)-cycloepoxydon has been accomplished from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone. A new cycloepoxydon related heptacyclic dimer has been prepared and characterized. [reaction: see text]
