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Related Experiment Videos

Secondary standardisation of 95mTc.

A V Harms1, M Baker, S M Jerome

  • 1National Physical Laboratory, Queens Road, Teddington, Middlesex TW11 0LW, UK. arvic.harms@npl.co.uk

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|February 28, 2004
PubMed
Summary

Technetium-95m (95mTc) can be produced via an alpha reaction with niobium-93. This method yields pure 95mTc, suitable for use as a yield tracer in radiochemical analysis of technetium-99.

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Area of Science:

  • Nuclear Chemistry
  • Radiochemistry
  • Analytical Chemistry

Background:

  • The long-lived fission product technetium-99 (99Tc) is challenging to quantify due to its low-energy beta emission.
  • Short-lived gamma-emitting radionuclides are valuable as yield tracers in radiochemical analysis.
  • Technetium-95m (95mTc) is a potential tracer for 99Tc due to its suitable half-life and gamma emissions.

Purpose of the Study:

  • To develop a production method for 95mTc.
  • To establish effective chemical separation techniques for 95mTc.
  • To standardize the produced 95mTc for use as a radiochemical yield tracer.

Main Methods:

  • Production of 95mTc via the (alpha, 2n) nuclear reaction using stable niobium-93 (93Nb) target.
  • Chemical separation of 95mTc from the niobium matrix using coprecipitation, liquid-liquid extraction, and liquid chromatography.

Related Experiment Videos

  • Secondary standardization of 95mTc using high-resolution gamma-ray spectrometry and an ionization chamber system.

    • Main Results:

    • Successful production of 95mTc via the 93Nb(alpha, 2n)95mTc reaction.
    • The production route avoids the formation of other technetium isotopes (97mTc, 98Tc, 99Tc).
    • Effective separation and standardization protocols for 95mTc were established.

    Conclusions:

    • The (alpha, 2n) reaction on 93Nb provides a reliable method for producing pure 95mTc.
    • The developed chemical separation and standardization techniques enable the use of 95mTc as a yield tracer.
    • This work facilitates accurate radiochemical analysis of the long-lived fission product 99Tc.