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Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent

Antonio Varnavas1, Lucia Lassiani, Valentina Valenta

  • 1Department of Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy. varnavas@units.it

European Journal of Medicinal Chemistry
|February 28, 2004
PubMed

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Cholinergic antagonists bind to cholinergic receptors and limit the effects of acetylcholine and other cholinergic agonists. Based on the specific cholinergic receptor affinity, these antagonists are classified as muscarinic or nicotinic. Anticholinergics interrupt parasympathetic innervations while sympathetic innervations remain uninterrupted. Muscarinic antagonists are also called 'muscarinic antagonists', 'antimuscarinics', or 'parasympatholytics'. Nicotinic antagonists are called...
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