Related Experiment Video
Updated: Aug 26, 2026
Experimental Assessment of Mouse Sociability Using an Automated Image Processing Approach
Published on: May 15, 2016
Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice
Edward S Brodkin1, Andrea Hagemann, Sondra Maureen Nemetski
1Department of Psychiatry, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Room 111, Philadelphia, PA 19104-6140, USA. ebrodkin@mail.med.upenn.edu
Abstract:
Little is known about the genetics of social approach-avoidance behaviors. We measured social approach-avoidance of prepubescent female C57BL/6J, DBA/2J, FVB/NJ, AKR/J, A/J, and BALB/cJ mice towards prepubescent DBA/2J female mice. C57BL/6J mice showed the greatest predominance of approach, while BALB/cJ mice showed the greatest predominance of avoidance. Thus, this phenotype is affected by spontaneous genetic variation in mice and can be measured in an assay useful for future neurogenetic studies.
