Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Predictors of atopic dermatitis severity over time.

Mohamed A Ben-Gashir1, Paul T Seed, Roderick J Hay

  • 1St John's Institute of Dermatology, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK. mbengashir@doctors.org.uk

Journal of the American Academy of Dermatology
|February 28, 2004
PubMed
Summary

Early-onset atopic dermatitis (AD) combined with asthma, hay fever, and urban living are linked to increased disease severity. Awareness of these factors can help predict outcomes for children with eczema.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LIFT: Lifting the Impacted fetal head; the Fetal Pillow<sup>®</sup> and Tydeman<sup>®</sup> Tube trial: protocol for a prospective observational study to evaluate two disimpaction devices.

BMC pregnancy and childbirth·2026
Same author

The natural history and evolution of dermatophytosis: Host immunity in acute and chronic infection.

PLoS pathogens·2026
Same author

Evaluating glycosylated fibronectin for rule-in and rule-out of pre-eclampsia in suspected cases.

Pregnancy hypertension·2026
Same author

Prediction of severe maternal and perinatal complications in hypertensive pregnancies using point-of-care glycosylated fibronectin: A prospective cohort study.

Pregnancy hypertension·2026
Same author

Emerging terbinafine-resistant Trichophyton indotineae between 2018 and 2023: a multinational genomic epidemiology study.

The Lancet. Microbe·2026
Same author

The Impact of Community-Based Midwife Continuity of Care Models for Women Living in Areas of Social Disadvantage and Ethnic Diversity in the United Kingdom: A Prospective Cohort Study.

BJOG : an international journal of obstetrics and gynaecology·2026

Area of Science:

  • Pediatric dermatology
  • Epidemiology of allergic diseases

Background:

  • Atopic dermatitis (AD) prevalence has risen significantly over the past four decades.
  • Factors influencing AD severity remain largely unknown.
  • Understanding these factors is crucial for managing this chronic condition.

Purpose of the Study:

  • To identify risk factors associated with atopic dermatitis severity in children.
  • To investigate the longitudinal progression of AD severity over a two-year period.
  • To provide insights for clinicians and researchers regarding disease outcomes.

Main Methods:

  • A longitudinal observational study involving 137 children aged 5-10 years in the UK.
  • Diagnosis of AD verified using UK diagnostic criteria.
  • Disease severity assessed using the Scoring AD index and parental questionnaires.

Related Experiment Videos

  • Nonparametric statistical tests used due to skewed severity score distribution.

    • Main Results:

    • Children with AD onset in the first year of life, co-occurring asthma/hay fever, and residing in urban areas showed more severe disease.
    • This association remained significant even after accounting for other potential risk factors.
    • The study achieved an 88% follow-up rate over two years.

    Conclusions:

    • Early-onset AD, allergic comorbidities, and urban residence are significant predictors of increased disease severity.
    • Clinicians should consider these factors for better patient management and outcome prediction.
    • Further research into AD severity determinants is warranted.