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Published on: September 7, 2013
The lack of a relationship between atopic dermatitis and nonmelanoma skin cancers
Michael E Ming1, Ross Levy, Ole Hoffstad
1Department of Dermatology, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA.
Background:
Very little has been published on whether a relationship exists between atopic dermatitis (AD) and skin cancer.
Objective:
The goal of this study was to investigate whether individuals with AD are more likely than other patients with dermatologic conditions to develop nonmelanoma skin cancer.
Methods:
This was a case-control, mailed-survey study.
Results:
Of those contacted, 69.8% (3207 of 4591) filled out the survey. Of the control patients, 18.4% (254) had a history of AD as defined by the United Kingdom Working Party diagnosis criteria and composed 13.7% (210) of the cases. The unadjusted odds ratio of AD to nonmelanoma skin cancer was 0.70 (95% confidence interval 0.57-0.85). After fully adjusting for age, sex, ethnicity, and topical steroid use the odds ratio was 0.78 (0.61, 0.98). Using different definitions of AD had little effect on this result.
Conclusions:
It does not appear that patients with a history of AD are more likely to develop nonmelanoma skin cancers than other patients with dermatologic conditions.
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