Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Determining the most optimal stage for embryo cryopreservation.

Anthony R Anderson1, Margaret L Weikert, Jack L Crain

  • 1Presbyterian Hospital Institute for Assisted Reproduction, 200 Hawthorne Lane, 6A-IVF, Charlotte, North Carolina, 28204, USA. Tranderson@novanthealth.org

Reproductive Biomedicine Online
|March 3, 2004
PubMed
Summary

Blastocyst freezing, on day 5, offers superior pregnancy, implantation, and survival rates compared to day 3 cleaved embryo freezing. This method optimizes outcomes and manages supernumerary embryos effectively.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technique to 'Map' Chromosomal Mosaicism at the Blastocyst Stage.

Cytogenetic and genome research·2016
Same author

Blastocyst euploidy and implantation rates in a young (<35 years) and old (≥35 years) presumed fertile and infertile patient population.

Fertility and sterility·2014
Same author

Comparison of aneuploidy, pregnancy and live birth rates between day 5 and day 6 blastocysts.

Reproductive biomedicine online·2014
Same author

Outcomes of blastocysts biopsied and vitrified once versus those cryopreserved twice for euploid blastocyst transfer.

Reproductive biomedicine online·2014
Same author

The origin, mechanisms, incidence and clinical consequences of chromosomal mosaicism in humans.

Human reproduction update·2014
Same author

Reduction of high order multiples in frozen embryo transfers.

Reproductive biomedicine online·2005

Area of Science:

  • Reproductive Medicine
  • Embryology
  • Cryobiology

Background:

  • Embryo cryopreservation is a key component of assisted reproductive technologies.
  • Determining the optimal stage for embryo cryopreservation impacts success rates.

Purpose of the Study:

  • To compare the efficacy of cryopreservation for cleaved embryos (Day 3) versus blastocysts (Day 5).
  • To identify the optimal timing for embryo cryopreservation to maximize pregnancy outcomes.

Main Methods:

  • Retrospective analysis of frozen embryo transfer cycles.
  • Comparison of outcomes for Day 3 cleaved embryo transfers versus Day 5 blastocyst transfers.

Main Results:

  • Blastocyst freezing demonstrated significantly higher ongoing pregnancy, implantation, and post-thaw survival rates compared to cleaved embryo freezing.

Related Experiment Videos

  • No significant difference in ongoing pregnancy rates between fresh and frozen-thawed blastocyst transfers.
  • Day 5 blastocyst transfers resulted in a higher proportion of cryopreserved supernumerary embryos than Day 3 transfers.

    • Conclusions:

    • Cryopreservation of blastocysts is a viable and effective strategy for improving pregnancy outcomes.
    • Blastocyst freezing optimizes the management of supernumerary embryos and enhances per oocyte retrieval success rates.