Beating heart coronary artery bypass surgery after orthotopic heart transplantation

Minoru Ono1, Robert E Michler

  • 1Division of Cardiothoracic Surgery, Ohio State University College of Medicine, Columbus, Ohio, USA.

Insights

This study reports successful off-pump coronary artery bypass surgery for accelerated transplant coronary artery disease in a heart transplant recipient. The beating-heart procedure provided symptom relief and improved graft patency, offering a viable treatment option.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Transplantation

Background:

  • Accelerated transplant coronary artery disease (TAD) is a significant long-term complication following orthotopic heart transplantation.
  • TAD can progress rapidly, leading to graft dysfunction and patient morbidity.

Observation:

  • A 52-year-old male heart transplant recipient developed rapidly progressing triple-vessel disease 10 years post-transplant.
  • Symptoms included worsening shortness of breath and chest pain due to TAD.

Findings:

  • The patient underwent successful off-pump coronary artery bypass surgery using the left internal mammary artery to the left anterior descending artery.
  • The circumflex artery was not amenable to grafting due to diffuse small vessel disease.
  • Postoperative angiography confirmed widely patent bypass graft, and the patient remained symptom-free at 1-year follow-up.

Implications:

  • Off-pump coronary artery bypass surgery can be an effective revascularization strategy for select heart transplant recipients with advanced TAD.
  • This approach offers a potential solution for managing complex coronary artery disease in the context of prior transplantation.
  • Maintaining graft patency and symptom relief is crucial for long-term outcomes in heart transplant patients with coronary complications.