Urinary proteins in four rodent species

1. Mean urinary protein concentration levels are significantly higher in male Peromyscus leucopus than females (98.4 and 72.4 mg/dl). 2. Only females showed a significant correlation between weight and urinary protein concentration (r = 0.75 vs r = 0.03). 3. In intraspecific sexual electrophoretic comparisons of P. leucopus and P. maniculatus non-denatured urinary protein, four and two common bands were identified, respectively. Males of both species showed an extra protein band. 4. Four common electrophoretically separable denatured urinary protein bands were observed between 14,200 and 116,000 mol. wt in male and female P. leucopus and female P. gossypinus. Three of the four major protein bands were also found in P. maniculatus. Male Reithrodontomys megalotis pattern showed none of the major bands.