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Published on: March 27, 2018
Current status and outcomes of coronary revascularization 1999 to 2002: 148,396 surgical and percutaneous procedures
Michael J Mack1, Phillip P Brown, Aaron D Kugelmass
1Medical City Dallas Hospital, Dallas, Texas, USA. mjmack@earthlink.net
Insights
Percutaneous coronary intervention (PCI) is increasingly used for coronary artery disease over coronary artery bypass grafting (CABG). While CABG treats more complex cases, PCI shows lower mortality and complication rates, with outcomes continually improving.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Health Services Research
Background:
- Practices and outcomes for coronary revascularization via surgical (CABG) and percutaneous (PCI) interventions are evolving.
- Understanding current trends and early results is crucial for patient care and resource allocation.
Purpose of the Study:
- To analyze trends in PCI versus CABG utilization from 1999-2002.
- To compare early outcomes, including mortality and complications, between PCI and CABG procedures.
- To assess the changing landscape of coronary artery disease interventions.
Main Methods:
- A retrospective analysis of 148,396 patients undergoing PCI or CABG across 69 hospitals.
- Data extracted from the HCA Casemix Database, utilizing ICD-9 coding for conditions and outcomes.
- Logistic regression was employed to calculate odds ratios for death and complications, adjusting for numerous patient and procedural factors.
Main Results:
- PCI volume increased by 6.8% annually, becoming 65.4% of all coronary revascularizations, while CABG volume declined.
- PCI was predominantly used for single-vessel disease (83%), whereas CABG focused on multivessel disease (3.38 bypasses/patient).
- PCI patients experienced lower unadjusted mortality (1.25% vs. 2.63%) and significantly fewer acute renal failure, neurologic, and cardiac complications compared to CABG patients.
Conclusions:
- PCI utilization continues to rise relative to CABG for coronary artery disease treatment.
- Despite CABG treating more complex multivessel disease, PCI demonstrates superior safety profiles with lower mortality and complication rates.
- The disparity in adverse outcomes between CABG and PCI is narrowing, indicating ongoing improvements in both intervention types.
Background:
Current practice, trends, and early outcomes in patients undergoing surgical and percutaneous coronary interventions (PCI) are changing and subject to speculation.
Methods:
148,396 consecutive patients in 69 HCA, Inc hospitals who underwent either PCI or coronary artery bypass grafting (CABG) were tracked in the HCA Casemix Database from 1999 through the first quarter of 2002. Comorbid conditions, procedures, complications, and outcome variables were defined through International Classification of Diseases, Ninth Revision coding. Odds ratios (OR) for death and other procedure-related complications were estimated using logistic regression adjusting for age, sex, and 31 other patient clinical and procedural characteristics.
Results:
Now 65.4% of all coronary revascularization is by PCI with a 6.8% annual rate of increase whereas CABG volume is declining by 1.9% per year. However the majority of these changes occurred between 1999 and 2000 with only small changes in the last 3 years. Coronary artery bypass grafting is still utilized primarily for multivessel disease (3.38 bypasses per patient) whereas PCI is predominately (83%) still limited to single-vessel intervention. Unadjusted mortality rates over the full 13-quarter period were 1.25% for PCI and 2.63% for CABG (p < 0.001), with PCI rates remaining constant and CABG mortality declining. Twenty-three percent of CABG is performed off pump with a lower mortality than conventional on-pump CABG (2.37% versus 2.69%, p < 0.001). Percutaneous coronary intervention patients have lower mortality (OR 0.51), and fewer acute renal failure (OR 0.39), neurologic (OR 0.12), and cardiac (OR 0.16) complications than CABG patients (p < 0.001).
Conclusions:
Interventions for coronary artery disease continue to rise primarily due to an increase in PCI. The volume of PCI continues to increase relative to CABG. Although adverse outcomes are higher after CABG, the proportion of multivessel disease treated is greater. The difference in adverse outcomes between CABG and PCI remains small and continues to decline.
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