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Related Experiment Videos

Cross talk: interview with Al Gilman.

A G Gilman

    Molecular Interventions
    |March 3, 2004
    PubMed
    Summary
    This summary is machine-generated.

    Alfred Goodman Gilman leads a major initiative to map cell signaling pathways. This collaborative project aims to build a comprehensive database for a "virtual cell" model.

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    Area of Science:

    • Pharmacology
    • Cellular Biology
    • Systems Biology

    Background:

    • Alfred Goodman Gilman, a Nobel laureate, has dedicated his career to cell signaling research.
    • He has chaired the Department of Pharmacology at UT Southwestern for two decades.
    • His father co-authored a seminal pharmacology textbook in the year of his birth.

    Discussion:

    • The Alliance for Cellular Signaling, directed by Gilman, is a ten-year research program.
    • It involves numerous leading investigators in the cell signaling field.
    • The project focuses on understanding input-output relationships in signaling cells.

    Key Insights:

    • A Nobel Prize was awarded to Gilman for his work on G proteins.
    • The initiative emphasizes the need for extensive collaboration within the scientific community.

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  • A central goal is to create a comprehensive database for a "virtual cell".

    • Outlook:

    • The project aims to provide a complete understanding of cellular signaling.
    • Success relies on broad participation and data sharing from the signaling community.
    • The findings will contribute to advancements in pharmacology and cellular biology.