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LySDB - Lysozyme Structural DataBase.

K Samaya Mohan1, Soma Das, C Chockalingam

  • 1Bioinformatics Centre, Indian Institute of Science, Bangalore 560 012, India.

Acta Crystallographica. Section D, Biological Crystallography
|March 3, 2004
PubMed
Summary
This summary is machine-generated.

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LySDB is a database of 740 lysozyme structures, offering 3D visualization and search tools for researchers. It provides updated structural information for lysozyme proteins.

Area of Science:

  • Biochemistry
  • Structural Biology
  • Bioinformatics

Background:

  • Lysozyme is a crucial enzyme with diverse biological functions.
  • Access to comprehensive structural data is essential for understanding enzyme mechanisms.
  • Existing resources may lack integrated visualization and search capabilities for lysozyme structures.

Purpose of the Study:

  • To develop and present LySDB, an integrated database for lysozyme structural information.
  • To provide tools for visualizing and analyzing 3D lysozyme structures.
  • To offer an up-to-date repository of lysozyme structural data.

Main Methods:

  • Compiled 740 three-dimensional lysozyme structures from the Protein Data Bank.
  • Integrated a search engine with visualization facilities.

Related Experiment Videos

  • Utilized the RASMOL program for 3D structure visualization.
  • Ensured regular updates of structural data from scientific literature.

    • Main Results:

    • LySDB offers visualization of entire protein models and specific substructures.
    • The database includes a search engine with multiple functionalities.
    • Users can access current lysozyme structural data through the web.

    Conclusions:

    • LySDB serves as a valuable, accessible resource for researchers studying lysozyme.
    • The database facilitates detailed analysis of lysozyme's 3D structure and variations.
    • Continuous updates ensure LySDB remains a relevant tool for the scientific community.