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[Experimental study on bioglass application in extending alveolar bone crest in rabbit]
1Stomatological Hospital of Shandong University, Jinan 250012, Shandong province, China.
Objective:
To observe the effect of Bioglass guiding bone regeneration and forming normal new bone in extending alveolar bone crest by surgery.
Methods:
Thirty-six rabbits were randomly divided into three groups. The first group was treated with Bioglass and the second with hudroxyapectite (HA). The third group was control group. At 4 8 12 weeks after surgery, the condition of bone regeneration was observed with radiological and pathological methods.
Results:
Statistical analysis showed that there was a significant difference between the third group and the other two groups (P<0.05). In addition, Bioglass can guide bone regeneration faster than hydroxyapatite, and it can be substituted by new bone to form completely normal bone.
Conclusion:
Since Bioglass is more effective than HA in guiding bone regeneration, it is an ideal bone graft substitute.
