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Updated: Aug 6, 2026

Development and Evaluation of a Rat Model of Full-Thickness Cartilage Defects
Published on: May 19, 2023
[Establishment of an animal model of osteochondral defect by arthroscope in TMJ]
1Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Second Medical University, Shanghai, 200011, China.
Objective:
To create an animal model of osteochondral defect in temporomandibular joint (TMJ) by arthroscope to minimize the surgical injury.
Methods:
Subchondral drilling on the anterior slope of condyle and posterior slope of eminence were performed on 12 rhesus monkeys (24 joints) by arthroscope.
Results:
The osteochondral defect models of TMJ were successfully made on 12 monkeys (24 joints).
Conclusion:
There are fewer injuries and bias in the animal models of TMJ osteochondral defect by arthroscope than by open surgery.

