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Updated: Aug 7, 2026
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
[An experimental study on arthroscopic chondrocytes transplantation for repair of osteochondral defects in TMJ]
1Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Second Medical University, Shanghai, 200011 China.
Objective:
To certify the feasibility of arthroscopic chondrocytes transplantation in temporomandibular joint (TMJ) and the nature of repaired tissue with autologous chondrocytes transplantation in osteochondral defects.
Methods:
The animal models of osteochondral defects in TMJ were established in 12 rhesus monkeys. Autologous auricular chondrocytes were transplanted to the defects by arthroscope. Healing of the defects was assessed by gross examination, light microscope, immunohistochemical staining.
Results:
The repaired tissues with chondrocytes transplantation were fibrocartilages.
Conclusion:
The technique of arthroscopic chondrocytes transplantation is feasible and the nature of repaired tissue is closest to the normal cartilage, compared with those of subchondral drilling and cartilage transplantation.
