Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anticoagulation for atrial fibrillation.

Margaret C Fang1, Daniel E Singer

  • 1University of California, San Francisco, 533 Parnassus Avenue, Box 0131, San Francisco, CA 94143, USA. mfang@medicine.ucsf.edu

Cardiology Clinics
|March 5, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Contribution of Social and Economic Factors to Accelerated Biological Aging Differences Between Non-Hispanic Black and White Adults in the Health and Retirement Study.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026
Same author

Atrial Fibrillation and Stroke Prevention and Management in Chronic Kidney Disease.

Clinical journal of the American Society of Nephrology : CJASN·2026
Same author

Bleeding-related quality of life in older adults: Psychometric evaluation of the HEmorrhage Life Impact indeX (HELIX).

Thrombosis research·2026
Same author

Utility of Risk Scores for Predicting Stroke and Intracranial Bleeding Across Levels of Kidney Function in Two Large Community-Based Cohorts of Older Adults With Atrial Fibrillation.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same author

Right-Sizing Thromboprophylaxis in Medical Inpatients.

JAMA network open·2026
Same author

Patterns of antithrombotic treatment after left atrial appendage occlusion.

Heart rhythm·2026

Atrial fibrillation (AF) significantly increases stroke risk, but oral anticoagulants like warfarin effectively prevent these strokes. Further research will refine antithrombotic strategies for AF patients.

Area of Science:

  • Cardiology
  • Neurology
  • Epidemiology

Background:

  • Atrial fibrillation (AF) is a significant risk factor for stroke, primarily due to atrio-embolic mechanisms.
  • Decades of research provide insights into AF-related stroke risks and prevention strategies.

Purpose of the Study:

  • To summarize current knowledge on AF-related stroke prevention.
  • To highlight the efficacy and safety of oral anticoagulants in managing AF.
  • To identify areas for future research in antithrombotic therapy for AF.

Main Methods:

  • Review of epidemiologic studies and randomized clinical trials.
  • Analysis of data on the effectiveness and safety of oral anticoagulants (e.g., warfarin).
  • Synthesis of evidence regarding anticoagulation management in clinical practice.

Related Experiment Videos

Main Results:

  • Oral anticoagulants, particularly warfarin targeting an INR of 2.5, effectively reduce AF-related stroke risk with good safety.
  • High-quality anticoagulation management is achievable in routine clinical settings.
  • Current strategies have significant implications for patient care and public health.

Conclusions:

  • Warfarin and similar anticoagulants are crucial for preventing AF-related strokes.
  • Effective anticoagulation management is feasible in standard clinical practice.
  • Future research should focus on refining stroke/hemorrhage risk assessment, optimizing antithrombotic use, and evaluating new therapies for AF.