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Related Concept Videos

Viscosity01:17

Viscosity

When water is poured into a glass, it falls freely and quickly, whereas if honey or maple syrup is poured over a pancake, it flows slowly and sticks to the surface of the container. This difference in the flow of different kinds of liquids arises due to the fluid friction between the liquid layers and the liquid and the surrounding material. This property of fluids is called fluid viscosity. In this example, water has a lower viscosity than honey and maple syrup.
The SI unit of viscosity is...
Fluid Pressure over Flat Plate of Variable Width01:02

Fluid Pressure over Flat Plate of Variable Width

When a flat plate is submerged in a fluid, the fluid exerts pressure on the plate. This pressure can lead to many different phenomena, including drag and buoyancy. To understand the behavior of the fluid over a flat plate of variable width, it is essential to analyze the distribution of the pressure exerted.
The pressure distribution on the plate can be calculated by determining the force that acts on a differential area strip of the plate. Thus, the magnitude of the force is equal to the...
Structure and Function of Platelets01:18

Structure and Function of Platelets

The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
Formation of the Platelet Plug01:22

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
Types of Fluids01:27

Types of Fluids

Fluids can be classified into Newtonian and non-Newtonian fluids based on their response to shear stress. Newtonian fluids have a linear relationship between shear stress and the shear strain rate, following Newton's law of viscosity. Their viscosity remains constant regardless of the shear rate, making their behavior predictable and easier to analyze. Common examples include water, air, oil, and gasoline.
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and their...
Steady, Laminar Flow Between Parallel Plates01:17

Steady, Laminar Flow Between Parallel Plates

Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.

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Updated: Jul 26, 2026

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
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Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

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Bulk and interfacial properties of binary hard-platelet fluids.

M Bier1, L Harnau, S Dietrich

  • 1Max-Planck-Institut für Metallforschung, Heisenbergstrasse 3, D-70569 Stuttgart, Germany. bier@fluids.mpi-stuttgart.mpg.de

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|March 5, 2004
PubMed
Summary

Density-functional theory reveals complex interfacial behaviors in binary hard platelet mixtures. Findings include density inversion and complete wetting phenomena, offering insights into fluid phase behavior.

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Last Updated: Jul 26, 2026

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
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Published on: March 19, 2016

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A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

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Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

Area of Science:

  • Physical Chemistry
  • Soft Matter Physics
  • Materials Science

Background:

  • Understanding fluid phase behavior in mixtures is crucial for materials design.
  • Hard platelet systems exhibit complex phase diagrams and interfacial phenomena.
  • Existing models often simplify particle shapes and interactions.

Purpose of the Study:

  • To investigate interfacial properties of binary hard platelet mixtures.
  • To explore density and orientational order parameter profiles at phase interfaces.
  • To determine interfacial tension and wetting behavior using advanced theoretical methods.

Main Methods:

  • Utilizing density-functional theory (DFT) for theoretical analysis.
  • Implementing a fundamental measure theory (FMT) adapted to the Zwanzig model.
  • Calculating excess free energy functionals for confined systems.
  • Simulating particle orientations restricted to three orthogonal orientations.

Main Results:

  • Observed density inversion and oscillatory density profiles in specific mixtures.
  • Identified a Fisher-Widom line, indicating capillary wave-driven demixing.
  • Found lowest interfacial tension when platelets orient parallel to the interface.
  • Discovered complete wetting of isotropic-nematic interfaces by a second nematic phase in certain systems.

Conclusions:

  • DFT and FMT provide accurate predictions for hard platelet mixture interfaces.
  • Platelet shape, size, and orientation significantly influence interfacial properties.
  • The study elucidates fundamental mechanisms governing phase separation and wetting in confined systems.