Related Experiment Video

Updated: Aug 6, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
08:48

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Published on: October 13, 2011

Stretching of proteins in the entropic limit

Marek Cieplak1, Trinh Xuan Hoang, Mark O Robbins

  • 1Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, Maryland 21218, USA.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|March 5, 2004
PubMed

More Related Videos

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation12:26

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation

Published on: February 12, 2022

Related Concept Videos

Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
Elasticity01:12

Elasticity

Elasticity is the ability of an object to withstand the effects of distortion and to return to its original size and shape once the forces causing deformation are removed. When an elastic material deforms under the action of an external force, it experiences internal resistance to the deformation. However, if no external force is applied, it returns to its original state.
The elasticity of an object can be described by a stress-strain curve, which represents the relationship between stress...
Entropy and the Second Law of Thermodynamics01:20

Entropy and the Second Law of Thermodynamics

The second law of thermodynamics can be stated quantitatively using the concept of entropy. Entropy is the measure of disorder of the system.
The relation  between entropy and disorder can be illustrated with the example of the phase change of ice to water. In ice, the molecules are located at specific sites giving a solid state, whereas, in a liquid form, these molecules are much freer to move. The molecular arrangement has therefore become more randomized. Although the change in average...
Hooke's Law01:26

Hooke's Law

Hooke's law, a pivotal principle in material science, establishes that the strain a material undergoes is directly proportional to the applied stress, defined by a factor called the modulus of elasticity or Young's modulus.
The Squeeze Theorem01:30

The Squeeze Theorem

Certain mathematical functions exhibit unpredictable or highly variable behavior near specific input values, making direct evaluation of their limits challenging. This complexity may arise from rapid oscillations or irregular patterns that obscure the function’s trend. In such cases, the Squeeze Theorem offers a reliable method for determining limits.According to the Squeeze Theorem, if a function is confined between two other functions near a particular point, and both outer functions approach...