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Cell Type-specific Gene Expression Profiling in the Mouse Liver
Published on: September 17, 2019
Rat liver BiP/GRP78 is down-regulated by a peroxisome-proliferator, clofibrate
1Department of Biochemistry, School of Pharmaceutical Sciences, Toho University, Chiba, Japan.
FEBS Letters
|August 17, 1992
Abstract:
Administration of clofibrate in rat results in down-regulation of several liver proteins and a vast induction of peroxisomal proteins. One protein was identified as BiP/GRP78 using antibodies and cDNA cloning. The level of mRNA was reduced by the drug.
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