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[Primary amoebic meningoencephalitis: a case report].

O Cubero-Menéndez¹, D Cubero-Rego

¹Departamento de Anatomía Patológica, Hospital Pediatrico Docente William Soler, La Habana, Cuba.

Revista De Neurologia

|March 5, 2004

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Primary amoebic meningoencephalitis caused by Naegleria fowleri is a rare and fatal infection. Diagnosis was only confirmed post-mortem, highlighting challenges in early detection of this severe CNS amoebic infection.

Area of Science:

Neurology
Infectious Diseases
Parasitology

Background:

Free-living amoeba infections of the central nervous system (CNS) are globally rare.
These infections manifest as acute necrotizing hemorrhagic meningoencephalitis (nearly 100% fatality) or chronic granulomatous amoebic encephalitis.

Observation:

A case of fatal primary amoebic meningoencephalitis (PAM) caused by Naegleria fowleri in an 8-year-old child is presented.
The child had a history of freshwater reservoir immersion 52 hours prior to death.

Findings:

Pre-mortem laboratory studies failed to establish a diagnosis.
Amoeba trophozoites were identified during the post-mortem examination, confirming the diagnosis.

Implications:

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This case underscores the diagnostic challenges associated with Naegleria fowleri infections.
Early and accurate diagnosis is critical for potential therapeutic interventions in CNS amoebic infections.